Required clinicals: 

• Have a positive skin test or in vitro reactivity to a perennial aeroallergen.

• Baseline plasma immunoglobulin E (IgE) level w/in the following ranges as determined by age and weight in kg (see PI for full chart):

  • Adult (12+yrs) 30 IU/ml – 700 Iu/ml

  • Pediatric (6-12yrs) 30 IU/ml – 1300 IU/ml

  • FEV1 less than 80% predicted