Required clinicals: 

• Ultomiris REMS enrollment

• Proof of meningococcal vaccination at least 2 weeks prior to start of treatment (If urgent Ultomiris therapy is indicated in an unvaccinated patient, administer meningococcal vaccine(s) as soon as possible and provide patients with two weeks of antibacterial drug prophylaxis

• Serum anti-acetylcholine receptor (AChR) antibody-positive